AFM/TIRF force clamp measurements of neurosecretory vesicle tethers reveal characteristic unfolding steps.

AFM/TIRF force clamp measurements of neurosecretory vesicle tethers reveal characteristic unfolding steps.

Although several proteins have been implicated in secretory vesicle tethering, the identity and mechanical properties of the components forming the physical vesicle-plasma membrane link remain unknown. Here we present the first experimental measurements of nanomechanical properties of secretory vesi...

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Bibliographic Details
Main Authors: Mark C Harris, Dillon Cislo, Joan S Lenz, Christopher Umbach, Manfred Lindau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5360256?pdf=render

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http://europepmc.org/articles/PMC5360256?pdf=render

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