miR-15b-5p targeting amyloid precursor protein is involved in the anti-amyloid eflect of curcumin in swAPP695-HEK293 cells

miR-15b-5p targeting amyloid precursor protein is involved in the anti-amyloid eflect of curcumin in swAPP695-HEK293 cells

Curcumin exerts a neuroprotective effect on Alzheimer’s disease; however, it is not known whether microRNAs are involved in this protective effect. This study was conducted using swAPP695-HEK293 cells as an Alzheimer’s disease cell model. swAPP695-HEK293 cells were treated with 0, 0.5, 1, 2, 5, and...

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Bibliographic Details
Main Authors: Hong-Ying Liu, Xian Fu, You-Fu Li, Xian-Liang Li, Zhen-Yu Ma, Ying Zhang, Qing-Chun Gao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; Alzheimer′s disease; natural plant drug; curcuminoids; miRNAs; amyloid precursor protein; amyloid-β; 3?-untranslated region; Luciferase assays; neurons; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=9;spage=1603;epage=1609;aulast=Liu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=9;spage=1603;epage=1609;aulast=Liu

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