Chemogenetic activation of PVN CRH neurons disrupts the estrous cycle and LH dynamics in female mice

Chemogenetic activation of PVN CRH neurons disrupts the estrous cycle and LH dynamics in female mice

IntroductionThe impact of stress on reproductive function is significant. Hypothalamic paraventricular nucleus (PVN) corticotrophin-releasing hormone (CRH) plays a major role in regulating the stress response. Understanding how the hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pitui...

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Bibliographic Details
Main Authors: Junru Yu, Xiao-Feng Li, Krasimira Tsaneva-Atanasova, Eder Zavala, Kevin T. O’Byrne
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Endocrinology
Subjects:
PVN
CRH
estrous cycle
LH
CORT
mathematical model
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1322662/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1322662/full

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