Human apical-out nasal organoids reveal an essential role of matrix metalloproteinases in airway epithelial differentiation

Human apical-out nasal organoids reveal an essential role of matrix metalloproteinases in airway epithelial differentiation

Abstract Extracellular matrix (ECM) assembly/disassembly is a critical regulator for airway epithelial development and remodeling. Airway organoid is widely used in respiratory research, yet there is limited study to indicate the roles and mechanisms of ECM organization in epithelial growth and diff...

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Bibliographic Details
Main Authors: Liyue Li, Linyi Jiao, Danni Feng, Yizhang Yuan, Xiaoqian Yang, Jian Li, Dong Jiang, Hexin Chen, Qingxiang Meng, Ruchong Chen, Bixing Fang, Xuenong Zou, Zhenhua Luo, Xiaoyan Ye, Yue Hong, Chun Liu, Chunwei Li
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44488-1

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https://doi.org/10.1038/s41467-023-44488-1

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