Limited Oxidative Stress Favors Resistance to Skeletal Muscle Atrophy in Hibernating Brown Bears (<i>Ursus Arctos</i>)

Limited Oxidative Stress Favors Resistance to Skeletal Muscle Atrophy in Hibernating Brown Bears (<i>Ursus Arctos</i>)

Oxidative stress, which is believed to promote muscle atrophy, has been reported to occur in a few hibernators. However, hibernating bears exhibit efficient energy savings and muscle protein sparing, despite long-term physical inactivity and fasting. We hypothesized that the regulation of the oxidan...

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Bibliographic Details
Main Authors: Blandine Chazarin, Anna Ziemianin, Alina L. Evans, Emmanuelle Meugnier, Emmanuelle Loizon, Isabelle Chery, Jon M. Arnemo, Jon E. Swenson, Guillemette Gauquelin-Koch, Chantal Simon, Stéphane Blanc, Etienne Lefai, Fabrice Bertile
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Antioxidants
Subjects:
hibernation
brown bears
skeletal muscle
cold response
oxidative stress
NRF2
Online Access:https://www.mdpi.com/2076-3921/8/9/334

Internet

https://www.mdpi.com/2076-3921/8/9/334

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