Multicentre, multi-arm, double-blind randomised placebo-controlled dose-finding trial investigating the safety and Efficacy of MirococePt (APT070) In Reducing delayed graft function In the Kidney ALlograft (EMPIRIKAL-2): study protocol for a randomised controlled trial

Background Up to 50% of kidney transplant patients are diagnosed with delayed graft function (DGF) following transplantation—the majority being linked to ischaemia reperfusion injury (IRI). DGF is traditionally defined as the requirement for dialysis during the first week after transplantation and i...

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Main Authors: Richard Smith, Abdel Douiri, Simon Knight, Abbas Ghazanfar, Alima Rahman, Steven Sacks, Peter Friend, Marc Delord, Fayyad Jaradat, Theodoros Kassimatis, Roseanna Greenlaw, Joanne Palmer Joyce, Jonathon Olsburgh, Muhammad Khurram, Sapna Shah, Hannah Killbride
Format: Article
Language:English
Published: BMJ Publishing Group 2025-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/3/e097029.full