Design and Evaluation of Dissolving Microneedles for Enhanced Dermal Delivery of Propranolol Hydrochloride

Design and Evaluation of Dissolving Microneedles for Enhanced Dermal Delivery of Propranolol Hydrochloride

Oral propranolol hydrochloride has been the first-line treatment for infantile hemangioma (IH), whereas systemic exposure to propranolol has the potential of causing serious adverse reactions. Dermal delivery of propranolol is preferable due to high local drug concentration and fewer adverse effects...

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Bibliographic Details
Main Authors: Jingjing He, Zichen Zhang, Xianzi Zheng, Lu Li, Jianping Qi, Wei Wu, Yi Lu
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
microneedles
propranolol hydrochloride
dermal delivery
hyaluronic acid
polyvinyl pyrrolidone
infantile hemangioma
Online Access:https://www.mdpi.com/1999-4923/13/4/579

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https://www.mdpi.com/1999-4923/13/4/579

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