Rafoxanide sensitizes colorectal cancer cells to TRAIL-mediated apoptosis

Rafoxanide sensitizes colorectal cancer cells to TRAIL-mediated apoptosis

Colorectal cancer (CRC) remains a leading causes of cancer-related death in the world, mainly due to the lack of effective treatment of advanced disease. TNF-related apoptosis-inducing ligand (TRAIL)-driven cell death, a crucial event in the control of tumor growth, selectively targets malignant rat...

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Bibliographic Details
Main Authors: Federica Laudisi, Teresa Pacifico, Claudia Maresca, Anderson Luiz-Ferreira, Sara Antonelli, Angela Ortenzi, Alfredo Colantoni, Antonio Di Grazia, Eleonora Franzè, Marco Colella, Davide Di Fusco, Giuseppe S. Sica, Ivan Monteleone, Giovanni Monteleone, Carmine Stolfi
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Drug repurposing
Endoplasmic reticulum stress
DR5
C-FLIP
Survivin
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222011830

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http://www.sciencedirect.com/science/article/pii/S0753332222011830

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