Cerebral net uptake of lactate contributes to neurological injury after experimental cardiac arrest in rabbits

Cerebral net uptake of lactate contributes to neurological injury after experimental cardiac arrest in rabbits

Abstract During focal ischemia, neurons can use lactate as an alternative source of energy through its oxidation into pyruvate by the lactate dehydrogenase (LDH). After cardiac arrest, the neurological consequences of this phenomenon are unknown. Experimental study. Experimental laboratory. Male New...

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Bibliographic Details
Main Authors: Estelle Faucher, Alexandra Demelos, Emilie Boissady, Yara Abi Zeid Daou, Fanny Lidouren, Bernard Vigué, Aurore Rodriguez, Bijan Ghaleh, Renaud Tissier, Matthias Kohlhauer
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Cardiac arrest
Lactate
Neuroprotection
Astrocytes
Oxamate
Fluorocitrate
Online Access:https://doi.org/10.1038/s41598-024-74660-6

Internet

https://doi.org/10.1038/s41598-024-74660-6

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