New Insights into the Behavior of NHC-Gold Complexes in Cancer Cells

New Insights into the Behavior of NHC-Gold Complexes in Cancer Cells

Among the non-platinum antitumor agents, gold complexes have received increased attention owing to their strong antiproliferative effects, which generally occur through non-cisplatin-like mechanisms of action. Several studies have revealed that many cytotoxic gold compounds, such as N-heterocyclic c...

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Bibliographic Details
Main Authors: Giuseppa Augello, Antonina Azzolina, Filomena Rossi, Filippo Prencipe, Giuseppe Felice Mangiatordi, Michele Saviano, Luisa Ronga, Melchiorre Cervello, Diego Tesauro
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
NHC-gold(I) complexes
TrxR1 activity
antiproliferative effect
cancer cells
Online Access:https://www.mdpi.com/1999-4923/15/2/466

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https://www.mdpi.com/1999-4923/15/2/466

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