Functional determinants of protein assembly into homomeric complexes

Abstract Approximately half of proteins with experimentally determined structures can interact with other copies of themselves and assemble into homomeric complexes, the overwhelming majority of which (>96%) are symmetric. Although homomerisation is often assumed to a functionally beneficial resu...

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Bibliographic Details
Main Authors: L. Therese Bergendahl, Joseph A. Marsh
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05084-8