Generation of long tracts of disease-associated DNA repeats
The generation of long uninterrupted DNA repeats is important for the study of repeat instability associated with several human genetic diseases, including myotonic dystrophy type 1. However, obtaining defined lengths of long repeats in vitro has been problematic. Strand slippage and/or DNA secondar...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2005-02-01
|
Series: | BioTechniques |
Online Access: | https://www.future-science.com/doi/10.2144/05382RR01 |