Identification of Endocrine-Disrupting Compounds Using Nanoelectrospray Ionization Mass Spectrometry

Identification of Endocrine-Disrupting Compounds Using Nanoelectrospray Ionization Mass Spectrometry

A method using chip-based nanoelectrospray mass spectrometry (nanoESI-MS) is described to detect noncovalent ligand binding to the human estrogen receptor alpha ligand-binding domain (hER? LBD). This system represents an important environmental interest, because a wide variety of molecules...

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Bibliographic Details
Main Authors: Cédric Bovet, Marc Ruff, Arno Wortmann, Sylvia Eiler, Florence Granger, Bertran Gerrits, Dino Moras, Renato Zenobi
Format: Article
Language:deu
Published: Swiss Chemical Society 2008-05-01
Series:CHIMIA
Subjects:
Electrospray ionization mass spectrometry
Endochrine-disrupting compounds
Estrogen receptor
Noncovalent
Solution-binding affinity
Online Access:https://chimia.ch/chimia/article/view/4490

Internet

https://chimia.ch/chimia/article/view/4490

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