Characterization of Two Novel Bacteriophages Infecting Multidrug-Resistant (MDR) Acinetobacter baumannii and Evaluation of Their Therapeutic Efficacy in Vivo

Characterization of Two Novel Bacteriophages Infecting Multidrug-Resistant (MDR) Acinetobacter baumannii and Evaluation of Their Therapeutic Efficacy in Vivo

Acinetobacter baumannii is emerging as a challenging nosocomial pathogen due to its rapid evolution of antibiotic resistance. We report characterization of two novel bacteriophages, PBAB08 and PBAB25, infecting clinically isolated, multidrug-resistant (MDR) A. baumannii strains. Both phages belonged...

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Bibliographic Details
Main Authors: Kyoungeun Cha, Hynu K. Oh, Jae Y. Jang, Yunyeol Jo, Won K. Kim, Geon U. Ha, Kwan S. Ko, Heejoon Myung
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Microbiology
Subjects:
multidrug-resistance
Acinetobacter baumannii
bacteriophage therapy
mouse model
genome analysis
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00696/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00696/full

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