A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity.

A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity.

In order to promote infection, the blood-borne parasite Trypanosoma brucei releases factors that upregulate arginase expression and activity in myeloid cells.By screening a cDNA library of T. brucei with an antibody neutralizing the arginase-inducing activity of parasite released factors, we identif...

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Bibliographic Details
Main Authors: Géraldine De Muylder, Sylvie Daulouède, Laurence Lecordier, Pierrick Uzureau, Yannick Morias, Jan Van Den Abbeele, Guy Caljon, Michel Hérin, Philippe Holzmuller, Silla Semballa, Pierrette Courtois, Luc Vanhamme, Benoît Stijlemans, Patrick De Baetselier, Michael P Barrett, Jillian L Barlow, Andrew N J McKenzie, Luke Barron, Thomas A Wynn, Alain Beschin, Philippe Vincendeau, Etienne Pays
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3814429?pdf=render

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http://europepmc.org/articles/PMC3814429?pdf=render

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