A Phosphorylation Switch on Lon Protease Regulates Bacterial Type III Secretion System in Host

ABSTRACT Most pathogenic bacteria deliver virulence factors into host cytosol through type III secretion systems (T3SS) to perturb host immune responses. The expression of T3SS is often repressed in rich medium but is specifically induced in the host environment. The molecular mechanisms underlying...

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Bibliographic Details
Main Authors: Xiaofeng Zhou, Doron Teper, Maxuel O. Andrade, Tong Zhang, Sixue Chen, Wen-Yuan Song, Nian Wang
Format: Article
Language:English
Published: American Society for Microbiology 2018-03-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02146-17