Hypoxia inducible factor-1ɑ as a potential therapeutic target for osteosarcoma metastasis

Hypoxia inducible factor-1ɑ as a potential therapeutic target for osteosarcoma metastasis

Osteosarcoma (OS) is a malignant tumor originating from mesenchymal tissue. Pulmonary metastasis is usually present upon initial diagnosis, and metastasis is the primary factor affecting the poor prognosis of patients with OS. Current research shows that the ability to regulate the cellular microenv...

Full description

Bibliographic Details
Main Authors: Jianghu Zhou, Fengjun Lan, Miao Liu, Fengyan Wang, Xu Ning, Hua Yang, Hong Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
osteosarcoma
HIF-1ɑ
metastasis
cellular microenvironment
signaling pathways
therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1350187/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1350187/full

Similar Items