Long-Term Mixed Chimerism After Ex Vivo/In Vivo T Cell-Depleted Allogeneic Hematopoietic Cell Transplantation in Patients With Myeloid Neoplasms

Long-Term Mixed Chimerism After Ex Vivo/In Vivo T Cell-Depleted Allogeneic Hematopoietic Cell Transplantation in Patients With Myeloid Neoplasms

In patients who have undergone allogeneic hematopoietic cell transplantation (HCT), myeloid mixed donor chimerism (MC) is a risk factor for disease relapse. In contrast, several studies found favorable outcome in patients with lymphoid MC. Thus far, most studies evaluating MC focused on a short-term...

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Bibliographic Details
Main Authors: Leo Ruhnke, Friedrich Stölzel, Uta Oelschlägel, Malte von Bonin, Katja Sockel, Jan Moritz Middeke, Christoph Röllig, Korinna Jöhrens, Johannes Schetelig, Christian Thiede, Martin Bornhäuser
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Oncology
Subjects:
chimerism
mixed donor chimerism
allogeneic hematopoietic cell transplantation
myeloid neoplasms
AML
CML
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.776946/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.776946/full

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