Cholestatic liver diseases: new targets, new therapies

Cholestatic liver diseases result from gradual destruction of bile ducts, accumulation of bile acids and self-perpetuation of the inflammatory process leading to damage to cholangiocytes and hepatocytes. If left untreated, cholestasis will lead to fibrosis, biliary cirrhosis, and ultimately end-stag...

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Bibliographic Details
Main Authors: Priscila Santiago, Andrew R. Scheinberg, Cynthia Levy
Format: Article
Language:English
Published: SAGE Publishing 2018-08-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756284818787400