Differentially Detectable <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment

Differentially Detectable <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment

ABSTRACT Recent reports indicate that the sputum of 80% or more of treatment-naive subjects with tuberculosis recruited in England or South Africa contained more viable Mycobacterium tuberculosis cells detected by limiting dilution (LD) in liquid culture than detected as CFU. Efforts to generate suc...

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Bibliographic Details
Main Authors: Kathrine McAulay, Kohta Saito, Thulasi Warrier, Kathleen Frances Walsh, Laurent Daniel Mathurin, Gertrude Royal-Mardi, Myung Hee Lee, Oksana Ocheretina, Jean William Pape, Daniel W. Fitzgerald, Carl F. Nathan
Format: Article
Language:English
Published: American Society for Microbiology 2018-12-01
Series:mBio
Subjects:
Mycobacterium tuberculosis
differentially detectable bacteria
early bactericidal activity
rifampin
viable but nonculturable bacteria
Online Access:https://journals.asm.org/doi/10.1128/mBio.02192-18

Internet

https://journals.asm.org/doi/10.1128/mBio.02192-18

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