The Anti-Cancer Potency and Mechanism of a Novel Tumor-Activated Fused Toxin, DLM

Melittin, which acts as a membrane-disrupting lytic peptide, is not only cytotoxic to tumors, but also vital to normal cells. Melittin had low toxicity when coupled with target peptides. Despite significant research development with the fused toxin, a new fused toxin is needed which has a cleavable...

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Bibliographic Details
Main Authors: Dejun Sun, Miaonan Sun, Wenhe Zhu, Zhiding Wang, Yuefei Li, Jie Ma
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/2/423