A comparative pharmacokinetic and pharmacodynamic study of two novel Cuban PEGylated rHuEPO versus MIRCERA® and ior®EPOCIM

A comparative pharmacokinetic and pharmacodynamic study of two novel Cuban PEGylated rHuEPO versus MIRCERA® and ior®EPOCIM

Context: The recombinant human erythropoietin (rHuEPO) stimulates the erythropoiesis process. Because this glycoprotein has a short half-life, it needs to be administrated two to three times a week. One of the technics to solve this issue is the PEGgilation. Aims: To evaluate the pharmacokinetics...

Full description

Bibliographic Details
Main Authors: Gledys Reynaldo, Leyanis Rodríguez, Roberto Menéndez, Joaquín Solazábal, Daniel Amaro, María de los A. Becquer, Yamila Colom, Haydee Gil, Juan C. Polo, Gilberto Castañeda, Braulio Jiménez-Vélez, Jorge Duconge, Eduardo M. Fernández-Sánchez
Format: Article
Language:English
Published: GarVal Editorial Ltda. 2018-05-01
Series:Journal of Pharmacy & Pharmacognosy Research
Subjects:
erythropoietin
non-compartmental analysis
PEGylated EPO
pharmacodynamics
pharmacokinetics
reticulocytes
Online Access:http://jppres.com/jppres/pdf/vol6/jppres17.342_6.3.179.pdf

Internet

http://jppres.com/jppres/pdf/vol6/jppres17.342_6.3.179.pdf

Similar Items