Filamin a binds to CCR2B and regulates its internalization.

The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. Employing the yeast two-hybrid system, we identified the actin-bindi...

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Bibliographic Details
Main Authors: Laura Minsaas, Jesús Planagumà, Michael Madziva, Beate F Krakstad, Míriam Masià-Balagué, Arieh A Katz, Anna M Aragay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2923182?pdf=render