A coordinate-based co-localization index to quantify and visualize spatial associations in single-molecule localization microscopy

Abstract Visualizing the subcellular distribution of proteins and determining whether specific proteins co-localize is one of the main strategies in determining the organization and potential interactions of protein complexes in biological samples. The development of super-resolution microscopy tech...

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Bibliographic Details
Main Authors: Jelmer Willems, Harold D. MacGillavry
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08746-4