Regulation of CD47 expression on CD14+ monocytes by interferon-α in PBC patients

Regulation of CD47 expression on CD14+ monocytes by interferon-α in PBC patients

BackgroundPrimary biliary cholangitis (PBC) is a chronic intrahepatic cholestatic autoimmune liver disease characterized by inflammatory injury of small and medium-sized bile ducts in the liver. The pathogenesis of PBC has yet to be entirely understood. CD47/signal-regulatory protein alpha (SIRPα) i...

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Bibliographic Details
Main Authors: Xi Su, Wenwen Jin, Lizhi Liu, Zifei Zhu, Cunyan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
PBC
cd47
SIRPα
immune checkpoint
inflammatory response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1256995/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1256995/full

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