A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells.

We detected and characterized the binding sites of the representative Rest complex components Rest, Sin3A, and Lsd1. We compared their binding patterns in mouse embryonic stem (ES) cells and epiblast stem (EpiS) cells. We found few Rest sites unique to the EpiS cells. The ES-unique site features wer...

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Bibliographic Details
Main Authors: Masahide Seki, Hideki Masaki, Takako Arauchi, Hiromitsu Nakauchi, Sumio Sugano, Yutaka Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3994037?pdf=render