An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds

A synthetic route developed for the preparation of the A-ring of Taxol family of molecules is reported. By means of an intramolecular Diels-Alder reaction an asymmetric approach to this ring has been accomplished. Also, initial studies to prepare the A ring using an intramolecular Diels-Alder reacti...

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Bibliographic Details
Main Authors: M. L. Marin, D. Craig
Format: Article
Language:English
Published: MDPI AG 1998-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/3/3/64/