Root extract of Plumbago zeylanica L. induces cytotoxicity, inhibits cell migration and induces S-phase cell cycle arrest through down regulation of EGFR in HeLa cervical cancer cells

Root extract of Plumbago zeylanica L. induces cytotoxicity, inhibits cell migration and induces S-phase cell cycle arrest through down regulation of EGFR in HeLa cervical cancer cells

Plumbago zeylanica has been used in the traditional system of medicine from thousands of years owing to its potential therapeutic properties, however the anticancer and anti-metastatic effects are largely unknown against cervical cancer cells. In this study we demonstrated the cytotoxicity activity,...

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Bibliographic Details
Main Authors: Shubhasmita Mohapatra, Jasmine Mohanty, Sarita Pani, Sunitee Hansdah, Anil Kumar Biswal, Atish Kumar Sahoo, Priya Ranjan Debata
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Advances in Cancer Biology - Metastasis
Subjects:
Plumbago zeylanica
HeLa cells
MTT assay
Cell migration
S phase arrest
HRLC-MS plant Extract
Online Access:http://www.sciencedirect.com/science/article/pii/S2667394022000016

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http://www.sciencedirect.com/science/article/pii/S2667394022000016

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