Induction of CD36 and thrombospondin-1 in macrophages by hypoxia-inducible factor 1 and its relevance in the inflammatory process.

Induction of CD36 and thrombospondin-1 in macrophages by hypoxia-inducible factor 1 and its relevance in the inflammatory process.

Inflammation is part of a complex biological response of vascular tissue to pathogens or damaged cells. First inflammatory cells attempt to remove the injurious stimuli and this is followed by a healing process mediated principally by phagocytosis of senescent cells. Hypoxia and p38-MAPK are associa...

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Bibliographic Details
Main Authors: Dolores Ortiz-Masià, Irene Díez, Sara Calatayud, Carlos Hernández, Jesús Cosín-Roger, Joaquín Hinojosa, Juan V Esplugues, María D Barrachina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485304?pdf=render

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http://europepmc.org/articles/PMC3485304?pdf=render

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