Combination of Tanshinone IIA and Cisplatin Inhibits Esophageal Cancer by Downregulating NF-κB/COX-2/VEGF Pathway

Combination of Tanshinone IIA and Cisplatin Inhibits Esophageal Cancer by Downregulating NF-κB/COX-2/VEGF Pathway

Cisplatin (DDP) represents one of the common drugs used for esophageal squamous cell carcinoma (ESCC), but side effects associated with DDP and drug resistance lead to the failure of treatment. This study aimed to understand whether tanshinone IIA (tan IIA) and DDP could generate a synergistic antit...

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Bibliographic Details
Main Authors: Xiaozhong Liao, Ying Gao, Jiahui Liu, Lanting Tao, Jun Xie, Yueyu Gu, Taoli Liu, Dongmei Wang, Dan Xie, Suilin Mo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
Tan IIA
DDP
synergistic effect
ESCC
NF-κB/COX-2/VEGF pathway
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01756/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01756/full

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