Identification of MHC-I-Presented Porcine Respiratory and Reproductive Syndrome Virus (PRRSV) Peptides Reveals Immunogenic Epitopes within Several Non-Structural Proteins Recognized by CD8<sup>+</sup> T Cells

Identification of MHC-I-Presented Porcine Respiratory and Reproductive Syndrome Virus (PRRSV) Peptides Reveals Immunogenic Epitopes within Several Non-Structural Proteins Recognized by CD8<sup>+</sup> T Cells

Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most relevant porcine pathogens worldwide. Active control of the disease relies on modified live virus vaccines (MLVs), as most inactivated vaccines provide very limited protection. Neutralizing antibodies occur late in infect...

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Bibliographic Details
Main Authors: Marlene Mötz, Melissa R. Stas, Sabine E. Hammer, Tereza Duckova, Frederic Fontaine, Alexandra Kiesler, Kerstin Seitz, Andrea Ladinig, André C. Müller, Christiane Riedel, Armin Saalmüller, Till Rümenapf
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Viruses
Subjects:
porcine reproductive and respiratory syndrome virus
PRRSV
Arteriviridae
CD8<sup>+</sup> T cells
epitopes
swine leukocyte antigen class I
Online Access:https://www.mdpi.com/1999-4915/14/9/1891

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https://www.mdpi.com/1999-4915/14/9/1891

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