Clinical Response to Vedolizumab in Ulcerative Colitis Patients Is Associated with Changes in Integrin Expression Profiles

Clinical Response to Vedolizumab in Ulcerative Colitis Patients Is Associated with Changes in Integrin Expression Profiles

BackgroundDespite large clinical success, deeper insights into the immunological effects of vedolizumab therapy for inflammatory bowel diseases are scarce. In particular, the reasons for differential clinical response in individual patients, the precise impact on the equilibrium of integrin-expressi...

Full description

Bibliographic Details
Main Authors: Friederike Fuchs, Daniela Schillinger, Raja Atreya, Simon Hirschmann, Sarah Fischer, Clemens Neufert, Imke Atreya, Markus F. Neurath, Sebastian Zundler
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
inflammatory bowel diseases
ulcerative colitis
T cells
vedolizumab
integrins
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00764/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00764/full

Similar Items