Does positioning of chromosomes 8 and 21 in interphase drive t(8;21) in acute myelogenous leukemia?
The impact of chromosome architecture in the formation of chromosome aberrations is a recent finding of interphase directed molecular cytogenetic studies. There evidence was provided that disease specific chromosomal translocations could be due to tissue specific genomic organization. In a recent sm...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Pensoft Publishers
2012-10-01
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Series: | BioDiscovery |
Subjects: | |
Online Access: | https://biodiscovery.pensoft.net/article/8934/download/pdf/ |