A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions

A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions

Polyetheretherketone (PEEK) is a desirable alternative to conventional biomedical metals for orthopedic implants due to the excellent mechanical properties. However, the inherent bioinertness of PEEK contributes to inferior osseointegration of PEEK implants, especially under pathological conditions...

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Bibliographic Details
Main Authors: Yanyan Zheng, Ang Gao, Jiaxiang Bai, Qing Liao, Yuzheng Wu, Wei Zhang, Min Guan, Liping Tong, Dechun Geng, Xin Zhao, Paul K. Chu, Huaiyu Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-08-01
Series:Bioactive Materials
Subjects:
Polyetheretherketone
Surface modification
Osteoimmunomodulation
Sequential release
Osteoporosis
Osseointegration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22000573

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http://www.sciencedirect.com/science/article/pii/S2452199X22000573

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