Tissue inhibitor of matrix metalloprotinase-1 and collagen type IV in HCV-associated cirrhosis and grading of esophageal varices

Abstract Background Esophageal varices are abnormally dilated submucosal veins of the esophagus which develop as a result of portal hypertension due to cirrhosis. Collagen type IV is upregulated with a 14-fold increase in cirrhosis. Tissue inhibitor of metalloproteinases-1 (TIMP-1) is also upregulat...

Full description

Bibliographic Details
Main Authors: Nasser Mohamed Abdalla, Fatma Mohamed Abd El Aziz, Akram Deghady, Mohamed Helmy Abaza, Walid Ismail Ellakany
Format: Article
Language:English
Published: SpringerOpen 2024-02-01
Series:Egyptian Liver Journal
Subjects:
Online Access:https://doi.org/10.1186/s43066-024-00316-9