The Mutational Landscape of Acute Promyelocytic Leukemia Reveals an Interacting Network of Co-Occurrences and Recurrent Mutations.

The Mutational Landscape of Acute Promyelocytic Leukemia Reveals an Interacting Network of Co-Occurrences and Recurrent Mutations.

Preliminary Acute Promyelocytic Leukemia (APL) whole exome sequencing (WES) studies have identified a huge number of somatic mutations affecting more than a hundred different genes mainly in a non-recurrent manner, suggesting that APL is a heterogeneous disease with secondary relevant changes not ye...

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Bibliographic Details
Main Authors: Mariam Ibáñez, José Carbonell-Caballero, Luz García-Alonso, Esperanza Such, Jorge Jiménez-Almazán, Enrique Vidal, Eva Barragán, María López-Pavía, Marta LLop, Iván Martín, Inés Gómez-Seguí, Pau Montesinos, Miguel A Sanz, Joaquín Dopazo, José Cervera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4757557?pdf=render

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http://europepmc.org/articles/PMC4757557?pdf=render

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