Down-regulation of CD9 by methylation decreased bortezomib sensitivity in multiple myeloma.

Bortezomib therapy has been proven successful for the treatment of relapsed and/or refractory multiple myeloma (MM). However, both intrinsic and acquired resistance has already been observed. In this study, we explored the relationship between CD9 expression and bortezomib sensitivity in MM. We foun...

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Bibliographic Details
Main Authors: Xiaotong Hu, Han Xuan, Huaping Du, Hao Jiang, Jinwen Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095765&type=printable