Aerosolized delivery of ESKAPE pathogens for murine pneumonia models

Abstract Murine pneumonia models for ESKAPE pathogens serve to evaluate novel antibacterials or to investigate immunological responses. The majority of published models uses intranasal or to a limited extent the intratracheal instillation to challenge animals. In this study, we propose the aerosol d...

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Bibliographic Details
Main Authors: Katharina Rox, Eva Medina
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52958-9