Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle

Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle

Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle mass due to imbalance between protein synthesis and degradation, which is related with poor prognosis and compromised quality of life. Dysfunctional mitochondria are associated with lower muscle strength and muscl...

Full description

Bibliographic Details
Main Authors: Gabriela S. de Castro, Estefania Simoes, Joanna D.C.C. Lima, Milene Ortiz-Silva, William T. Festuccia, Flávio Tokeshi, Paulo S. Alcântara, José P. Otoch, Dario Coletti, Marilia Seelaender
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
cancer cachexia
skeletal muscle
mitochondria
autophagy
apoptosis
Online Access:https://www.mdpi.com/2072-6694/11/9/1264

Internet

https://www.mdpi.com/2072-6694/11/9/1264

Similar Items