The Chicken Chorioallantoic Membrane Tumor Assay as a Relevant In Vivo Model to Study the Impact of Hypoxia on Tumor Progression and Metastasis

The Chicken Chorioallantoic Membrane Tumor Assay as a Relevant In Vivo Model to Study the Impact of Hypoxia on Tumor Progression and Metastasis

Hypoxia in the tumor microenvironment is a negative prognostic factor associated with tumor progression and metastasis, and therefore represents an attractive therapeutic target for anti-tumor therapy. To test the effectiveness of novel hypoxia-targeting drugs, appropriate preclinical models that re...

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Bibliographic Details
Main Authors: Kelly Harper, Anna Yatsyna, Martine Charbonneau, Karine Brochu-Gaudreau, Alexis Perreault, Claudio Jeldres, Patrick P. McDonald, Claire M. Dubois
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
hypoxia
ChorioAllantoic Membrane
chick embryo
metastasis
tumor progression
Online Access:https://www.mdpi.com/2072-6694/13/5/1093

Internet

https://www.mdpi.com/2072-6694/13/5/1093

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