Snapshots of ABCG1 and ABCG5/G8: A Sterol’s Journey to Cross the Cellular Membranes

Snapshots of ABCG1 and ABCG5/G8: A Sterol’s Journey to Cross the Cellular Membranes

The subfamily-G ATP-binding cassette (ABCG) transporters play important roles in regulating cholesterol homeostasis. Recent progress in the structural data of ABCG1 and ABCG5/G8 disclose putative sterol binding sites that suggest the possible cholesterol translocation pathway. ABCG1 and ABCG5/G8 sha...

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Bibliographic Details
Main Authors: Fatemeh Rezaei, Danny Farhat, Gonca Gursu, Sabrina Samnani, Jyh-Yeuan Lee
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
ABCG1
ABCG5
ABCG8
structural motif
sterol trasportation
TICE
Online Access:https://www.mdpi.com/1422-0067/24/1/484

Internet

https://www.mdpi.com/1422-0067/24/1/484

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