Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos

Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos

The regulation of transcription requires the coordination of numerous activities on DNA, yet how transcription factors mediate these activities remains poorly understood. Here, we use lattice light-sheet microscopy to integrate single-molecule and high-speed 4D imaging in developing Drosophila embry...

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Bibliographic Details
Main Authors: Mustafa Mir, Michael R Stadler, Stephan A Ortiz, Colleen E Hannon, Melissa M Harrison, Xavier Darzacq, Michael B Eisen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-12-01
Series:eLife
Subjects:
single molecule imaging
zelda
bicoid
ms2
transcription regulation
membraneless compartments
Online Access:https://elifesciences.org/articles/40497

Internet

https://elifesciences.org/articles/40497

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