Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease

Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease

Circulating biomarkers reflecting cardiac inflammation are needed to improve the diagnostics and guide the treatment of heart failure patients. The cardiac production and shedding of the transmembrane proteoglycan syndecan-4 is upregulated by innate immunity signaling pathways. Here, we investigated...

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Bibliographic Details
Main Authors: Mari E. Strand, Maarten Vanhaverbeke, Michiel T. H. M. Henkens, Maurits A. Sikking, Karoline B. Rypdal, Bjørn Braathen, Vibeke M. Almaas, Theis Tønnessen, Geir Christensen, Stephane Heymans, Ida G. Lunde
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomedicines
Subjects:
proteoglycan
extracellular matrix
biomarker
heart failure
fibrosis
immunotherapy
Online Access:https://www.mdpi.com/2227-9059/11/4/1066

Internet

https://www.mdpi.com/2227-9059/11/4/1066

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