Regulation of cullin RING E3 ubiquitin ligases by CAND1 in vivo.

Cullin RING ligases are multi-subunit complexes consisting of a cullin protein which forms a scaffold onto which the RING protein Rbx1/2 and substrate receptor subunits assemble. CAND1, which binds to cullins that are not conjugated with Nedd8 and not associated with substrate receptors, has been sh...

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Bibliographic Details
Main Authors: Yee Shin Chua, Boon Kim Boh, Wanpen Ponyeam, Thilo Hagen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3020946?pdf=render