A Novel V1a Receptor Antagonist Blocks Vasopressin-induced Changes in the CNS Response to Emotional Stimuli: an fMRI Study

A Novel V1a Receptor Antagonist Blocks Vasopressin-induced Changes in the CNS Response to Emotional Stimuli: an fMRI Study

Background: We hypothesized that RX246, a vasopressin V1a receptor antagonist, blocks the effect of intranasally administered vasopressin on brain processing of angry Ekman faces. An interaction of intranasal and oral drug was predicted in the amygdala. Methods: Twenty-nine consenting right handed h...

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Bibliographic Details
Main Authors: Royce J Lee, Emil F Coccaro, Henk eCremers, Rosemary eMcCarron, Shi-fang eLu, MIchael eBrownstein, Neal G Simon
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Systems Neuroscience
Subjects:
Amygdala
Anger
Depression
Neuropeptides
Vasopressins
fMRI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00100/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00100/full

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