Factors released by low and high-LET irradiated fibroblasts modulate migration and invasiveness of pancreatic cancer cells

Factors released by low and high-LET irradiated fibroblasts modulate migration and invasiveness of pancreatic cancer cells

IntroductionRadiotherapy represents a major treatment option for patients with pancreatic cancer, however, its benefits remain limited also due to the ability of cancer cells to migrate to the surrounding tissues. Low-LET ionizing radiation is well known to promote tumor cell migration and invasion,...

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Bibliographic Details
Main Authors: Alexandra Charalampopoulou, Amelia Barcellini, Mario Ciocca, Riccardo Di Liberto, Francesca Pasi, Marco Giuseppe Pullia, Ester Orlandi, Angelica Facoetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
tumor microenvironment
pancreatic cancer
low-LET
high-LET
carbon ions
migration
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1003494/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1003494/full

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