Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR

Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR

Objectives: Although antiretroviral therapy (ART) effectively suppresses HIV-1 replication, it does not eradicate the virus and ART interruption consistently results in rebound of viraemia, demonstrating the persistence of a long-lived viral reservoir. Several approaches aimed at reducing virus pers...

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Bibliographic Details
Main Authors: Maud Mavigner, S. Thera Lee, Jakob Habib, Cameron Robinson, Guido Silvestri, Una O’Doherty, Ann Chahroudi
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Journal of Virus Eradication
Subjects:
SIV
integration
reservoir
latency
rhesus macaques
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664020308700

Internet

http://www.sciencedirect.com/science/article/pii/S2055664020308700

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