Disorder driven allosteric control of protein activity

Studies of protein allostery increasingly reveal an involvement of the back and forth order-disorder transitions in this mechanism of protein activity regulation. Here, we investigate the allosteric mechanisms mediated by structural disorder using the structure-based statistical mechanical model of...

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Bibliographic Details
Main Authors: Wei-Ven Tee, Enrico Guarnera, Igor N. Berezovsky
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Current Research in Structural Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X20300192