A Toxoplasma gondii patatin-like phospholipase contributes to host cell invasion.

Toxoplasma gondii is an obligate intracellular parasite that can invade any nucleated cell of any warm-blooded animal. In a previous screen to identify virulence determinants, disruption of gene TgME49_305140 generated a T. gondii mutant that could not establish a chronic infection in mice. The prot...

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Bibliographic Details
Main Authors: Sarah K Wilson, Justine Heckendorn, Bruno Martorelli Di Genova, Lindsey L Koch, Peggy J Rooney, Naomi Morrissette, Maryse Lebrun, Laura J Knoll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008650&type=printable