Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial

Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial

Abstract Background Postoperative pulmonary complications (PPCs) increase the morbidity and mortality of surgery in obese patients. High levels of positive end-expiratory pressure (PEEP) with lung recruitment maneuvers may improve intraoperative respiratory function, but they can also compromise hem...

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Main Authors: T. Bluth, R. Teichmann, T. Kiss, I. Bobek, J. Canet, G. Cinnella, L. De Baerdemaeker, C. Gregoretti, G. Hedenstierna, S. N. Hemmes, M. Hiesmayr, M. W. Hollmann, S. Jaber, J. G. Laffey, M. J. Licker, K. Markstaller, I. Matot, G. Müller, G. H. Mills, J. P. Mulier, C. Putensen, R. Rossaint, J. Schmitt, M. Senturk, A. Serpa Neto, P. Severgnini, J. Sprung, M. F. Vidal Melo, H. Wrigge, M. J. Schultz, P. Pelosi, M. Gama de Abreu, for the PROBESE investigators, and the PROtective VEntilation Network (PROVEnet), on behalf of the Clinical Trial Network of the European Society of Anaesthesiology (ESA)
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Trials
Subjects:
Mechanical ventilation
Positive end-expiratory pressure
Recruitment maneuver
Obesity
Postoperative pulmonary complication
Online Access:http://link.springer.com/article/10.1186/s13063-017-1929-0

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http://link.springer.com/article/10.1186/s13063-017-1929-0

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